The Epithelial and Stromal Immune Microenvironment in Gastric Cancer: A Comprehensive Analysis Reveals Prognostic Factors with Digital Cytometry

SIMPLE SUMMARY: We investigated the tumor microenvironment of gastric cancer (GC) by combining single cell and bulk transcriptomic profiles. We built a novel signature matrix to dissect epithelium and stroma signals from tissue samples using a scRNA-seq data set for GC and then applied cell mixture...

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Detalles Bibliográficos
Autores principales: Shen, Wenjun, Wang, Guoyun, Cooper, Georgia R., Jiang, Yuming, Zhou, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582557/
https://www.ncbi.nlm.nih.gov/pubmed/34771544
http://dx.doi.org/10.3390/cancers13215382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582557/
https://www.ncbi.nlm.nih.gov/pubmed/34771544
http://dx.doi.org/10.3390/cancers13215382

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