Folic Acid-Appended Hydroxypropyl-β-Cyclodextrin Exhibits Potent Antitumor Activity in Chronic Myeloid Leukemia Cells via Autophagic Cell Death

SIMPLE SUMMARY: 2-Hydroxypropyl-β-cyclodextrin (HP-β-CyD) is a cyclic oligosaccharide widely used as an excipient in pharmaceutical preparations, in addition to also being used as a cholesterol regulator. HP-β-CyD was used in clinical trials for patients with Niemann-Pick Type C disease to remove ac...

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Detalles Bibliográficos
Autores principales: Hoshiko, Toshimi, Kubota, Yasushi, Onodera, Risako, Higashi, Taishi, Yokoo, Masako, Motoyama, Keiichi, Kimura, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582559/
https://www.ncbi.nlm.nih.gov/pubmed/34771576
http://dx.doi.org/10.3390/cancers13215413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582559/
https://www.ncbi.nlm.nih.gov/pubmed/34771576
http://dx.doi.org/10.3390/cancers13215413

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