Enhancement of NK Cell Antitumor Effector Functions Using a Bispecific Single Domain Antibody Targeting CD16 and the Epidermal Growth Factor Receptor

SIMPLE SUMMARY: Strategies to enhance the preferential accumulation and activation of Natural Killer (NK) cells in the tumor microenvironment can be expected to increase the efficacy of NK cell-based cancer immunotherapy. In this study, we report that a bispecific single domain antibody (VHH) that t...

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Detalles Bibliográficos
Autores principales: Toffoli, Elisa C., Sheikhi, Abdolkarim, Lameris, Roeland, King, Lisa A., van Vliet, Amanda, Walcheck, Bruce, Verheul, Henk M. W., Spanholtz, Jan, Tuynman, Jurriaan, de Gruijl, Tanja D., van der Vliet, Hans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582566/
https://www.ncbi.nlm.nih.gov/pubmed/34771609
http://dx.doi.org/10.3390/cancers13215446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582566/
https://www.ncbi.nlm.nih.gov/pubmed/34771609
http://dx.doi.org/10.3390/cancers13215446

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