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Enhancement of NK Cell Antitumor Effector Functions Using a Bispecific Single Domain Antibody Targeting CD16 and the Epidermal Growth Factor Receptor
SIMPLE SUMMARY: Strategies to enhance the preferential accumulation and activation of Natural Killer (NK) cells in the tumor microenvironment can be expected to increase the efficacy of NK cell-based cancer immunotherapy. In this study, we report that a bispecific single domain antibody (VHH) that t...
Autores principales: | Toffoli, Elisa C., Sheikhi, Abdolkarim, Lameris, Roeland, King, Lisa A., van Vliet, Amanda, Walcheck, Bruce, Verheul, Henk M. W., Spanholtz, Jan, Tuynman, Jurriaan, de Gruijl, Tanja D., van der Vliet, Hans J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582566/ https://www.ncbi.nlm.nih.gov/pubmed/34771609 http://dx.doi.org/10.3390/cancers13215446 |
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