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Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice

Clinical evidence suggests that rapid and sustained antidepressant action can be attained with a single exposure to psychedelics. However, the biological substrates and key mediators of psychedelics’ enduring action remain unknown. Here, we show that a single administration of the psychedelic DOI pr...

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Detalles Bibliográficos
Autores principales: Revenga, Mario de la Fuente, Zhu, Bohan, Guevara, Christopher A., Naler, Lynette B., Saunders, Justin M., Zhou, Zirui, Toneatti, Rudy, Sierra, Salvador, Wolstenholme, Jennifer T., Beardsley, Patrick M., Huntley, George W., Lu, Chang, González-Maeso, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582597/
https://www.ncbi.nlm.nih.gov/pubmed/34686347
http://dx.doi.org/10.1016/j.celrep.2021.109836