The Use of Induced Pluripotent Stem Cells to Study the Effects of Adenosine Deaminase Deficiency on Human Neutrophil Development

Inherited defects that abrogate the function of the adenosine deaminase (ADA) enzyme and consequently lead to the accumulation of toxic purine metabolites cause profound lymphopenia and severe combined immune deficiency. Additionally, neutropenia and impaired neutrophil function have been reported a...

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Detalles Bibliográficos
Autores principales: Tsui, Michael, Min, Weixian, Ng, Stephanie, Dobbs, Kerry, Notarangelo, Luigi D., Dror, Yigal, Grunebaum, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582638/
https://www.ncbi.nlm.nih.gov/pubmed/34777360
http://dx.doi.org/10.3389/fimmu.2021.748519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582638/
https://www.ncbi.nlm.nih.gov/pubmed/34777360
http://dx.doi.org/10.3389/fimmu.2021.748519

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