Topological Analysis of γH2AX and MRE11 Clusters Detected by Localization Microscopy during X-ray-Induced DNA Double-Strand Break Repair

SIMPLE SUMMARY: Super-resolution single-molecule localization microscopy (SMLM) allows the detection of cluster formation of phosphorylation sites and recruited repair proteins (e.g., MRE11) around DNA double-strand breaks induced by ionizing radiation. The spatial arrangement of these targets can b...

Descripción completa

Detalles Bibliográficos
Autores principales: Hahn, Hannes, Neitzel, Charlotte, Kopečná, Olga, Heermann, Dieter W., Falk, Martin, Hausmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582740/
https://www.ncbi.nlm.nih.gov/pubmed/34771723
http://dx.doi.org/10.3390/cancers13215561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582740/
https://www.ncbi.nlm.nih.gov/pubmed/34771723
http://dx.doi.org/10.3390/cancers13215561

Ejemplares similares