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Topological Analysis of γH2AX and MRE11 Clusters Detected by Localization Microscopy during X-ray-Induced DNA Double-Strand Break Repair

SIMPLE SUMMARY: Super-resolution single-molecule localization microscopy (SMLM) allows the detection of cluster formation of phosphorylation sites and recruited repair proteins (e.g., MRE11) around DNA double-strand breaks induced by ionizing radiation. The spatial arrangement of these targets can b...

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Detalles Bibliográficos
Autores principales:	Hahn, Hannes, Neitzel, Charlotte, Kopečná, Olga, Heermann, Dieter W., Falk, Martin, Hausmann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582740/ https://www.ncbi.nlm.nih.gov/pubmed/34771723 http://dx.doi.org/10.3390/cancers13215561

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