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The BRD9/7 Inhibitor TP-472 Blocks Melanoma Tumor Growth by Suppressing ECM-Mediated Oncogenic Signaling and Inducing Apoptosis

SIMPLE SUMMARY: Melanoma is an aggressive form of skin cancer and the leading cause of skin cancer-related deaths. Current therapies, including those targeting oncogenic pathways and immunotherapies, provide therapeutic benefits to only a subset of melanoma patients. Therefore, more options for ther...

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Detalles Bibliográficos
Autores principales: Mason, Lawrence David, Chava, Suresh, Reddi, Kiran Kumar, Gupta, Romi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582741/
https://www.ncbi.nlm.nih.gov/pubmed/34771678
http://dx.doi.org/10.3390/cancers13215516