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Targeted Deep Sequencing of Mycosis Fungoides Reveals Intracellular Signaling Pathways Associated with Aggressiveness and Large Cell Transformation

SIMPLE SUMMARY: In order to decipher the molecular mechanisms of large cell transformation (LCT) in mycosis fungoides (MF), we screened 51 longitudinally obtained skin samples of mycosis fungoides patients (n = 27) with versus without large-cell transformation by the means of targeted deep sequencin...

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Detalles Bibliográficos
Autores principales: Wobser, Marion, Roth, Sabine, Appenzeller, Silke, Houben, Roland, Schrama, David, Goebeler, Matthias, Geissinger, Eva, Rosenwald, Andreas, Maurus, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582785/
https://www.ncbi.nlm.nih.gov/pubmed/34771672
http://dx.doi.org/10.3390/cancers13215512