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Identification of Risk Loci for Radiotoxicity in Prostate Cancer by Comprehensive Genotyping of TGFB1 and TGFBR1

SIMPLE SUMMARY: Genetic variability in transforming growth factor beta pathway (TGFB) has been reported to affect adverse events in radiotherapy. We investigated 40 germline polymorphisms in peripheral blood cells, covering the entire common genetic variability in the TGFβ1 ligand (gene TGFB1) and t...

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Detalles Bibliográficos
Autores principales: Guhlich, Manuel, Hubert, Laura, Mergler, Caroline Patricia Nadine, Rave-Fraenk, Margret, Dröge, Leif Hendrik, Leu, Martin, Schmidberger, Heinz, Rieken, Stefan, Hille, Andrea, Schirmer, Markus Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582951/
https://www.ncbi.nlm.nih.gov/pubmed/34771749
http://dx.doi.org/10.3390/cancers13215585