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H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines

SIMPLE SUMMARY: Although the involvement of the H3.3K27M mutation in Diffuse Midline Glioma tumorigenesis is now established, its role in their resistance to treatments and, therefore, in their fatal outcome remains poorly documented. Here, thanks to our models of H3.3K27M induction in pediatric gli...

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Detalles Bibliográficos
Autores principales: Rakotomalala, Andria, Bailleul, Quentin, Savary, Clara, Arcicasa, Mélanie, Hamadou, Maud, Huchedé, Paul, Hochart, Audrey, Restouin, Audrey, Castellano, Remy, Collette, Yves, Dieny, Emma, Vincent, Audrey, Angrand, Pierre-Olivier, Le Bourhis, Xuefen, Leblond, Pierre, Furlan, Alessandro, Castets, Marie, Pasquier, Eddy, Meignan, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583077/
https://www.ncbi.nlm.nih.gov/pubmed/34771714
http://dx.doi.org/10.3390/cancers13215551