Cargando…
H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines
SIMPLE SUMMARY: Although the involvement of the H3.3K27M mutation in Diffuse Midline Glioma tumorigenesis is now established, its role in their resistance to treatments and, therefore, in their fatal outcome remains poorly documented. Here, thanks to our models of H3.3K27M induction in pediatric gli...
Autores principales: | Rakotomalala, Andria, Bailleul, Quentin, Savary, Clara, Arcicasa, Mélanie, Hamadou, Maud, Huchedé, Paul, Hochart, Audrey, Restouin, Audrey, Castellano, Remy, Collette, Yves, Dieny, Emma, Vincent, Audrey, Angrand, Pierre-Olivier, Le Bourhis, Xuefen, Leblond, Pierre, Furlan, Alessandro, Castets, Marie, Pasquier, Eddy, Meignan, Samuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583077/ https://www.ncbi.nlm.nih.gov/pubmed/34771714 http://dx.doi.org/10.3390/cancers13215551 |
Ejemplares similares
-
Evofosfamide Is Effective against Pediatric Aggressive Glioma Cell Lines in Hypoxic Conditions and Potentiates the Effect of Cytotoxic Chemotherapy and Ionizing Radiations
por: Bailleul, Quentin, et al.
Publicado: (2021) -
The Intricate Epigenetic and Transcriptional Alterations in Pediatric High-Grade Gliomas: Targeting the Crosstalk as the Oncogenic Achilles’ Heel
por: Huchedé, Paul, et al.
Publicado: (2022) -
Long survival in a child with a mutated K27M-H3.3 pilocytic astrocytoma
por: Hochart, Audrey, et al.
Publicado: (2015) -
Hypoxia in Solid Tumors: How Low Oxygenation Impacts the “Six Rs” of Radiotherapy
por: Rakotomalala, Andria, et al.
Publicado: (2021) -
The role of long non-coding RNAs in genome formatting and expression
por: Angrand, Pierre-Olivier, et al.
Publicado: (2015)