Manufacturing T cells in hollow fiber membrane bioreactors changes their programming and enhances their potency

Engineered T cell therapies have revolutionized modern oncology, however processes for manufacturing T cell therapies vary and the impact of manufacturing processes On the cell product is poorly understood. Herein, we have used a commercially available hollow fiber membrane bioreactor (HFMBR) operat...

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Detalles Bibliográficos
Autores principales: Yoo, Seung Mi, Lau, Vivan W.C., Aarts, Craig, Bojovic, Bojana, Steinberg, Gregory, Hammill, Joanne A., Dvorkin-Gheva, Anna, Ghosh, Raja, Bramson, Jonathan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583081/
https://www.ncbi.nlm.nih.gov/pubmed/34777917
http://dx.doi.org/10.1080/2162402X.2021.1995168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583081/
https://www.ncbi.nlm.nih.gov/pubmed/34777917
http://dx.doi.org/10.1080/2162402X.2021.1995168

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