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Manufacturing T cells in hollow fiber membrane bioreactors changes their programming and enhances their potency
Engineered T cell therapies have revolutionized modern oncology, however processes for manufacturing T cell therapies vary and the impact of manufacturing processes On the cell product is poorly understood. Herein, we have used a commercially available hollow fiber membrane bioreactor (HFMBR) operat...
Autores principales: | Yoo, Seung Mi, Lau, Vivan W.C., Aarts, Craig, Bojovic, Bojana, Steinberg, Gregory, Hammill, Joanne A., Dvorkin-Gheva, Anna, Ghosh, Raja, Bramson, Jonathan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583081/ https://www.ncbi.nlm.nih.gov/pubmed/34777917 http://dx.doi.org/10.1080/2162402X.2021.1995168 |
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