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Post-Hypoxic Cells Promote Metastatic Recurrence after Chemotherapy Treatment in TNBC

SIMPLE SUMMARY: Intratumoral hypoxia is a negative prognostic factor in breast cancer progression and recurrence. By implementing a hypoxia fate-mapping system, we followed cells that experience intratumoral hypoxia in vivo and determined that these cells have an increased ability to metastasize com...

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Detalles Bibliográficos
Autores principales: Godet, Inês, Mamo, Mahelet, Thurnheer, Andrea, Rosen, D. Marc, Gilkes, Daniele M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583122/
https://www.ncbi.nlm.nih.gov/pubmed/34771673
http://dx.doi.org/10.3390/cancers13215509