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The role of microglia in prion diseases and possible therapeutic targets: a literature review

Creutzfeldt-Jakob disease (CJD) is a rare and fatal condition that leads to progressive neurodegeneration due to gliosis, vacuolation of central nervous system tissue, and loss of neurons. Microglia play a crucial role in maintaining Central Nervous System (CNS) homoeostasis, both in health and dise...

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Detalles Bibliográficos
Autores principales: de Melo, Ananda Sampaio Lamenha Falcão, Lima, Juliana Louise Dias, Malta, Maria Carolina Silva, Marroquim, Natália França, Moreira, Álvaro Rivelli, de Almeida Ladeia, Isabelle, dos Santos Cardoso, Fabrizio, Gonçalves, Daniel Buzaglo, Dutra, Bruna Guimarães, dos Santos, Júlio César Claudino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583147/
https://www.ncbi.nlm.nih.gov/pubmed/34751640
http://dx.doi.org/10.1080/19336896.2021.1991771