Cargando…

The role of microglia in prion diseases and possible therapeutic targets: a literature review

Creutzfeldt-Jakob disease (CJD) is a rare and fatal condition that leads to progressive neurodegeneration due to gliosis, vacuolation of central nervous system tissue, and loss of neurons. Microglia play a crucial role in maintaining Central Nervous System (CNS) homoeostasis, both in health and dise...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Melo, Ananda Sampaio Lamenha Falcão, Lima, Juliana Louise Dias, Malta, Maria Carolina Silva, Marroquim, Natália França, Moreira, Álvaro Rivelli, de Almeida Ladeia, Isabelle, dos Santos Cardoso, Fabrizio, Gonçalves, Daniel Buzaglo, Dutra, Bruna Guimarães, dos Santos, Júlio César Claudino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583147/ https://www.ncbi.nlm.nih.gov/pubmed/34751640 http://dx.doi.org/10.1080/19336896.2021.1991771

Ejemplares similares

Vertical one-and-a-half syndrome in a patient with pecheron artery ischemia: A case report
por: Gonçalves, Daniel Buzaglo, et al.
Publicado: (2021)

Microglia in Prion Diseases: Angels or Demons?
por: Peggion, Caterina, et al.
Publicado: (2020)

Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain
por: Bradford, Barry M., et al.
Publicado: (2022)

A neuroprotective role for microglia in prion diseases
por: Zhu, Caihong, et al.
Publicado: (2016)

Loss of Homeostatic Microglia Signature in Prion Diseases
por: Wang, Yue, et al.
Publicado: (2022)

Esthetics outcomes in patients submitted to pterional craniotomy and its variants: A scoping review
por: Gonçalves, Daniel Buzaglo, et al.
Publicado: (2021)

Microglia are not required for prion-induced retinal photoreceptor degeneration
por: Striebel, James F., et al.
Publicado: (2019)

Neuroinflammation, Microglia, and Cell-Association during Prion Disease
por: Carroll, James A., et al.
Publicado: (2019)

Resistance Exercise and Whey Protein Supplementation Reduce Mechanical Allodynia and Spinal Microglia Activation After Acute Muscle Trauma in Rats
por: Rodrigues, Gusthavo, et al.
Publicado: (2021)

Transcriptomic Determinants of Scrapie Prion Propagation in Cultured Ovine Microglia
por: Muñoz-Gutiérrez, Juan F., et al.
Publicado: (2016)

The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity
por: Obst, Juliane, et al.
Publicado: (2017)

Inflammatory response of microglia to prions is controlled by sialylation of PrP(Sc)
por: Srivastava, Saurabh, et al.
Publicado: (2018)

Microglia have limited influence on early prion pathogenesis, clearance, or replication
por: Race, Brent, et al.
Publicado: (2022)

Sickle cell intrahepatic cholestasis unresponsive to exchange blood transfusion: a case report
por: Guimarães, Juliana Albano de, et al.
Publicado: (2017)

Development of a Protein-Rich By-Product by 2(3) Factorial Design: Characterization of Its Nutritional Value and Sensory Analysis
por: dos Santos, Thamara R., et al.
Publicado: (2022)

Posterior dislocation of the sternoclavicular joint: report of two cases()
por: Labronici, Pedro José, et al.
Publicado: (2016)

Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region
por: Dal Bom, Juliana Paghi, et al.
Publicado: (2019)

CD11c is not required by microglia to convey neuroprotection after prion infection
por: Carroll, James A., et al.
Publicado: (2023)

Analysis of the Chemical Modification of Dental Enamel Submitted to 35% Hydrogen Peroxide “In-Office” Whitening, with or without Calcium
por: Moreira, Rudá França, et al.
Publicado: (2017)

Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil
por: Sousa, Ivanildo P., et al.
Publicado: (2021)

A Computational Method to Propose Mutations in Enzymes Based on Structural Signature Variation (SSV)
por: Mariano, Diego César Batista, et al.
Publicado: (2019)

TREATMENT OF QUADRICEPS TENDON RUPTURE IN HEMODIALYSIS PATIENTS: A 2020 UPDATE
por: Malta, Luis Marcelo de Azevedo, et al.
Publicado: (2022)

Breastfeeding self-efficacy in adult women and its relationship with exclusive maternal breastfeeding
por: Monteiro, Juliana Cristina dos Santos, et al.
Publicado: (2020)

Differential role of CCR2 in the dynamics of microglia and perivascular macrophages during prion disease
por: Gómez-Nicola, Diego, et al.
Publicado: (2014)

Phagocytic Activities of Reactive Microglia and Astrocytes Associated with Prion Diseases Are Dysregulated in Opposite Directions
por: Sinha, Anshuman, et al.
Publicado: (2021)

Innate Immune Tolerance in Microglia Does Not Impact on Central Nervous System Prion Disease
por: Pal, Reiss, et al.
Publicado: (2022)

A 15-Year Time-series Study of Tooth Extraction in Brazil
por: Cunha, Maria Aparecida Goncalves de Melo, et al.
Publicado: (2015)

EFFICACY OF LOW-LEVEL LASER THERAPY ON FISTULA-IN-ANO TREATMENT
por: dos SANTOS, Carlos Henrique Marques, et al.
Publicado: (2021)

Non-pharmacological management of pediatric functional abdominal pain disorders: Current evidence and future perspectives
por: Cordeiro Santos, Maria Luísa, et al.
Publicado: (2022)

Components of Banisteriopsis caapi, a Plant Used in the Preparation of the Psychoactive Ayahuasca, Induce Anti-Inflammatory Effects in Microglial Cells
por: Santos, Beatriz Werneck Lopes, et al.
Publicado: (2022)

Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain
por: Navia-Pelaez, Juliana M., et al.
Publicado: (2021)

Masculinidades inerentes à política brasileira de saúde do homem
por: Cesaro, Bruna Campos De, et al.
Publicado: (2018)

Morphometric magnetic resonance imaging study of the quadriceps tendon in hemodialysis patients: comparison with non-dialyzed controls
por: Malta, Luis Marcelo de Azevedo, et al.
Publicado: (2022)

C-Reactive Protein Is Not Correlated With Endothelial Dysfunction in Overweight and Obese Women
por: Sampaio, Raphael Ribeiro, et al.
Publicado: (2013)

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease
por: Vicente-Rodríguez, Marta, et al.
Publicado: (2023)

Accuracy and reliability of the Pfeffer Questionnaire for the Brazilian elderly population
por: Dutra, Marina Carneiro, et al.
Publicado: (2015)

Investigation of mutations in the HBB gene using the 1,000 genomes database
por: Carlice-dos-Reis, Tânia, et al.
Publicado: (2017)

UHPLC-HRMS/MS on untargeted metabolomics: a case study with Copaifera (Fabaceae)
por: Antonio, Ananda da Silva, et al.
Publicado: (2021)

Traceability of animal protein byproducts in ruminants by multivariate analysis of isotope ratio mass spectrometry to prevent transmission of prion diseases
por: Ferreira, Rui Seabra, et al.
Publicado: (2019)

Optimization of the cultivation conditions of Bacillus licheniformis BCLLNF-01 for cellulase production
por: da Silva, Raquel Nascimento, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dnm37095t488ar6cgol55ml5a0