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Viro-antibody therapy: engineering oncolytic viruses for genetic delivery of diverse antibody-based biotherapeutics

Cancer therapeutics approved for clinical application include oncolytic viruses and antibodies, which evolved by nature, but were improved by molecular engineering. Both facilitate outstanding tumor selectivity and pleiotropic activities, but also face challenges, such as tumor heterogeneity and lim...

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Detalles Bibliográficos
Autores principales: Kontermann, Roland E., Ungerechts, Guy, Nettelbeck, Dirk M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583164/
https://www.ncbi.nlm.nih.gov/pubmed/34747345
http://dx.doi.org/10.1080/19420862.2021.1982447