CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma

Multiple myeloma (MM) is a hematological malignancy characterized by the presence of clonal plasma cells in the bone marrow niche. Despite significant therapeutic advances, MM remains incurable for the majority of patients. Targeted radionuclide therapy (TRNT) has emerged as a promising treatment op...

Descripción completa

Detalles Bibliográficos
Autores principales: De Veirman, Kim, Puttemans, Janik, Krasniqi, Ahmet, Ertveldt, Thomas, Hanssens, Heleen, Romao, Ema, Hose, Dirk, Goyvaert, Cleo, Vlummens, Philip, Muyldermans, Serge, Breckpot, Karine, Bruchertseifer, Frank, Morgenstern, Alfred, D’Huyvetter, Matthias, Devoogdt, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583167/
https://www.ncbi.nlm.nih.gov/pubmed/34777918
http://dx.doi.org/10.1080/2162402X.2021.2000699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583167/
https://www.ncbi.nlm.nih.gov/pubmed/34777918
http://dx.doi.org/10.1080/2162402X.2021.2000699

Ejemplares similares