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DisA Restrains the Processing and Cleavage of Reversed Replication Forks by the RuvAB-RecU Resolvasome

DNA lesions that impede fork progression cause replisome stalling and threaten genome stability. Bacillus subtilis RecA, at a lesion-containing gap, interacts with and facilitates DisA pausing at these branched intermediates. Paused DisA suppresses its synthesis of the essential c-di-AMP messenger....

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Detalles Bibliográficos
Autores principales: Gándara, Carolina, Torres, Rubén, Carrasco, Begoña, Ayora, Silvia, Alonso, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583203/
https://www.ncbi.nlm.nih.gov/pubmed/34768753
http://dx.doi.org/10.3390/ijms222111323