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Lower Spermatozoal PIWI-LIKE 1 and 2 Transcript Levels Are Significantly Associated with Higher Fertilization Rates in IVF

The four human PIWI-LIKE gene family members PIWI-LIKE 1–4 play a pivotal role in stem cell maintenance and transposon repression in the human germline. Therefore, dysregulation of these genes negatively influences the genetic stability of the respective germ cell and subsequent development and matu...

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Detalles Bibliográficos
Autores principales: Giebler, Maria, Greither, Thomas, Handke, Diana, Seliger, Gregor, Behre, Hermann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583392/
https://www.ncbi.nlm.nih.gov/pubmed/34768750
http://dx.doi.org/10.3390/ijms222111320