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Antisense Oligonucleotide-Mediated Splice Switching: Potential Therapeutic Approach for Cancer Mitigation

SIMPLE SUMMARY: Splicing is an important mechanism by which precursor mRNA is modified into mature mRNA. This splicing plays a major role in the generation of different proteins required for cells. Cancer cells modulate this splicing in such a way that it facilitates uncontrolled growth and survival...

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Detalles Bibliográficos
Autores principales: Raguraman, Prithi, Balachandran, Akilandeswari Ashwini, Chen, Suxiang, Diermeier, Sarah D., Veedu, Rakesh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583451/
https://www.ncbi.nlm.nih.gov/pubmed/34771719
http://dx.doi.org/10.3390/cancers13215555