Proteotoxic Stress as an Exploitable Vulnerability in Cells with Hyperactive AKT

Hyperactivity of serine-threonine kinase AKT is one of the most common molecular abnormalities in cancer, where it contributes to poor outcomes by facilitating the growth and survival of malignant cells. Despite its well-documented anti-apoptotic effects, hyperactivity of AKT is also known to be str...

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Detalles Bibliográficos
Autores principales: Babagana, Mahamat, Brown, Lorin R., Slabodkin, Hannah Z., Kichina, Julia V., Kandel, Eugene S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583472/
https://www.ncbi.nlm.nih.gov/pubmed/34768807
http://dx.doi.org/10.3390/ijms222111376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583472/
https://www.ncbi.nlm.nih.gov/pubmed/34768807
http://dx.doi.org/10.3390/ijms222111376

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