Enhancing the Therapeutic Effect of 2-(211)At-astato-α-methyl-L-phenylalanine with Probenecid Loading

SIMPLE SUMMARY: To enhance the therapeutic effect of 2-(211)At-astato-α-methyl-L-phenylalanine (2-(211)At-AAMP), a radiopharmaceutical for targeted alpha therapy, we evaluated the effect of probenecid loading on its biodistribution and therapeutic effect in mice. Probenecid preloading significantly...

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Detalles Bibliográficos
Autores principales: Hanaoka, Hirofumi, Ohshima, Yasuhiro, Suzuki, Hiroyuki, Sasaki, Ichiro, Watabe, Tadashi, Ooe, Kazuhiro, Watanabe, Shigeki, Ishioka, Noriko S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583516/
https://www.ncbi.nlm.nih.gov/pubmed/34771676
http://dx.doi.org/10.3390/cancers13215514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583516/
https://www.ncbi.nlm.nih.gov/pubmed/34771676
http://dx.doi.org/10.3390/cancers13215514

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