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Differential and Common Signatures of miRNA Expression and Methylation in Childhood Central Nervous System Malignancies: An Experimental and Computational Approach

SIMPLE SUMMARY: Epigenetic mechanisms, that are modifications of the genome without the presence of mutations, are known to play a crucial role in central nervous system (CNS) tumors during childhood. Two well-known epigenetic regulatory mechanisms include methylation and miRNA regulatory mechanisms...

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Detalles Bibliográficos
Autores principales: Lambrou, George I., Poulou, Myrto, Giannikou, Krinio, Themistocleous, Marios, Zaravinos, Apostolos, Braoudaki, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583574/
https://www.ncbi.nlm.nih.gov/pubmed/34771655
http://dx.doi.org/10.3390/cancers13215491