ATM Kinase Dead: From Ataxia Telangiectasia Syndrome to Cancer

SIMPLE SUMMARY: Ataxia telangiectasia mutated (ATM) protein plays a pivotal role in the DNA-damage response through activation of many different molecular targets. Mutations of the related gene cause Ataxia Telangiectasia (A-T) disease, characterized by neurodegeneration, immunodeficiency, and predi...

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Detalles Bibliográficos
Autores principales: Putti, Sabrina, Giovinazzo, Alessandro, Merolle, Matilde, Falchetti, Maria Laura, Pellegrini, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583659/
https://www.ncbi.nlm.nih.gov/pubmed/34771661
http://dx.doi.org/10.3390/cancers13215498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583659/
https://www.ncbi.nlm.nih.gov/pubmed/34771661
http://dx.doi.org/10.3390/cancers13215498

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