The Mutation in wbaP cps Gene Cluster Selected by Phage-Borne Depolymerase Abolishes Capsule Production and Diminishes the Virulence of Klebsiella pneumoniae

Klebsiella pneumoniae is considered one of the most critical multidrug-resistant pathogens and urgently requires new therapeutic strategies. Capsular polysaccharides (CPS), lipopolysaccharides (LPS), and exopolysaccharides (EPS) are the major virulence factors protecting K. pneumoniae against the im...

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Detalles Bibliográficos
Autores principales: Kaszowska, Marta, Majkowska-Skrobek, Grazyna, Markwitz, Pawel, Lood, Cédric, Jachymek, Wojciech, Maciejewska, Anna, Lukasiewicz, Jolanta, Drulis-Kawa, Zuzanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583740/
https://www.ncbi.nlm.nih.gov/pubmed/34768992
http://dx.doi.org/10.3390/ijms222111562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583740/
https://www.ncbi.nlm.nih.gov/pubmed/34768992
http://dx.doi.org/10.3390/ijms222111562

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