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The Mutation in wbaP cps Gene Cluster Selected by Phage-Borne Depolymerase Abolishes Capsule Production and Diminishes the Virulence of Klebsiella pneumoniae
Klebsiella pneumoniae is considered one of the most critical multidrug-resistant pathogens and urgently requires new therapeutic strategies. Capsular polysaccharides (CPS), lipopolysaccharides (LPS), and exopolysaccharides (EPS) are the major virulence factors protecting K. pneumoniae against the im...
Autores principales: | Kaszowska, Marta, Majkowska-Skrobek, Grazyna, Markwitz, Pawel, Lood, Cédric, Jachymek, Wojciech, Maciejewska, Anna, Lukasiewicz, Jolanta, Drulis-Kawa, Zuzanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583740/ https://www.ncbi.nlm.nih.gov/pubmed/34768992 http://dx.doi.org/10.3390/ijms222111562 |
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