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A single-amino-acid mutation at position 225 in hemagglutinin attenuates H5N6 influenza virus in mice

The highly pathogenic avian influenza H5N6 viruses are widely circulating in poultry and wild birds, and have caused 38 human infections including 21 deaths; however, the key genetic determinants of the pathogenicity of these viruses have yet to be fully investigated. Here, we characterized two H5N6...

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Detalles Bibliográficos
Autores principales: Kong, Xingtian, Guan, Lizheng, Shi, Jianzhong, Kong, Huihui, Zhang, Yaping, Zeng, Xianying, Tian, Guobin, Liu, Liling, Li, Chengjun, Kawaoka, Yoshihiro, Deng, Guohua, Chen, Hualan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583753/
https://www.ncbi.nlm.nih.gov/pubmed/34686117
http://dx.doi.org/10.1080/22221751.2021.1997340