Cargando…
A single-amino-acid mutation at position 225 in hemagglutinin attenuates H5N6 influenza virus in mice
The highly pathogenic avian influenza H5N6 viruses are widely circulating in poultry and wild birds, and have caused 38 human infections including 21 deaths; however, the key genetic determinants of the pathogenicity of these viruses have yet to be fully investigated. Here, we characterized two H5N6...
Autores principales: | Kong, Xingtian, Guan, Lizheng, Shi, Jianzhong, Kong, Huihui, Zhang, Yaping, Zeng, Xianying, Tian, Guobin, Liu, Liling, Li, Chengjun, Kawaoka, Yoshihiro, Deng, Guohua, Chen, Hualan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583753/ https://www.ncbi.nlm.nih.gov/pubmed/34686117 http://dx.doi.org/10.1080/22221751.2021.1997340 |
Ejemplares similares
-
Key Amino Acid Residues That Determine the Antigenic Properties of Highly Pathogenic H5 Influenza Viruses Bearing the Clade 2.3.4.4 Hemagglutinin Gene
por: Zhang, Yuancheng, et al.
Publicado: (2023) -
H3N2 avian influenza viruses detected in live poultry markets in China bind to human-type receptors and transmit in guinea pigs and ferrets
por: Guan, Lizheng, et al.
Publicado: (2019) -
A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs
por: Wang, Zeng, et al.
Publicado: (2017) -
Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China
por: Cui, Pengfei, et al.
Publicado: (2022) -
Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host
por: Gao, Yuwei, et al.
Publicado: (2009)