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Pharmacokinetic interaction between rhynchopylline and pellodendrine via CYP450 enzymes and P-gp

CONTEXT: Rhynchopylline and pellodendrine are major extractions of commonly used Chinese medicine in gynaecology. The interaction between these two compounds could affect treatment efficiency and even result in toxicity during their co-administration in gynaecological prescription. OBJECTIVE: The ph...

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Detalles Bibliográficos
Autores principales: Meng, Qingzhen, Cheng, Yongheng, Zhou, Cui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583760/
https://www.ncbi.nlm.nih.gov/pubmed/34757861
http://dx.doi.org/10.1080/13880209.2021.1999988