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RIF1 Links Replication Timing with Fork Reactivation and DNA Double-Strand Break Repair

Replication timing (RT) is a cellular program to coordinate initiation of DNA replication in all origins within the genome. RIF1 (replication timing regulatory factor 1) is a master regulator of RT in human cells. This role of RIF1 is associated with binding G4-quadruplexes and changes in 3D chromat...

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Detalles Bibliográficos
Autores principales: Blasiak, Janusz, Szczepańska, Joanna, Sobczuk, Anna, Fila, Michal, Pawlowska, Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583789/
https://www.ncbi.nlm.nih.gov/pubmed/34768871
http://dx.doi.org/10.3390/ijms222111440