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RIF1 Links Replication Timing with Fork Reactivation and DNA Double-Strand Break Repair
Replication timing (RT) is a cellular program to coordinate initiation of DNA replication in all origins within the genome. RIF1 (replication timing regulatory factor 1) is a master regulator of RT in human cells. This role of RIF1 is associated with binding G4-quadruplexes and changes in 3D chromat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583789/ https://www.ncbi.nlm.nih.gov/pubmed/34768871 http://dx.doi.org/10.3390/ijms222111440 |