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Diazoxide Needs Mitochondrial Connexin43 to Exert Its Cytoprotective Effect in a Cellular Model of CoCl(2)-Induced Hypoxia

Hypoxia is the leading cause of death in cardiomyocytes. Cells respond to oxygen deprivation by activating cytoprotective programs, such as mitochondrial connexin43 (mCx43) overexpression and the opening of mitochondrial K(ATP) channels, aimed to reduce mitochondrial dysfunction. In this study we us...

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Detalles Bibliográficos
Autores principales: Pecoraro, Michela, Marzocco, Stefania, Popolo, Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583808/
https://www.ncbi.nlm.nih.gov/pubmed/34769027
http://dx.doi.org/10.3390/ijms222111599