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Amino Acids 785, 787 of the Na(+)/H(+) Exchanger Cytoplasmic Tail Modulate Protein Activity and Tail Conformation

The mammalian Na(+)/H(+) exchanger isoform 1 (NHE1) is a plasma membrane protein ubiquitously present in humans. It regulates intracellular pH by removing an intracellular proton in exchange for an extracellular sodium. It consists of a 500 amino acid membrane domain plus a 315 amino acid, regulator...

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Detalles Bibliográficos
Autores principales: Li, Xiuju, Tu, Tommy, Quan, Sicheng, Quintero, Francisco J., Fahlman, Richard, Fliegel, Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583816/
https://www.ncbi.nlm.nih.gov/pubmed/34768780
http://dx.doi.org/10.3390/ijms222111349