Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L

After almost two years from its first evidence, the COVID-19 pandemic continues to afflict people worldwide, highlighting the need for multiple antiviral strategies. SARS-CoV-2 main protease (Mpro/3CLpro) is a recognized promising target for the development of effective drugs. Because single target...

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Detalles Bibliográficos
Autores principales: Costanzi, Elisa, Kuzikov, Maria, Esposito, Francesca, Albani, Simone, Demitri, Nicola, Giabbai, Barbara, Camasta, Marianna, Tramontano, Enzo, Rossetti, Giulia, Zaliani, Andrea, Storici, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583849/
https://www.ncbi.nlm.nih.gov/pubmed/34769210
http://dx.doi.org/10.3390/ijms222111779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583849/
https://www.ncbi.nlm.nih.gov/pubmed/34769210
http://dx.doi.org/10.3390/ijms222111779

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