Immune Synapse Residency of Orai1 Alters Ca(2+) Response of T Cells

CRAC, which plays important role in Ca(2+)-dependent T-lymphocyte activation, is composed of the ER-resident STIM1 and the plasma membrane Orai1 pore-forming subunit. Both accumulate at the immunological synapse (IS) between a T cell and an antigen-presenting cell (APC). We hypothesized that adapter...

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Detalles Bibliográficos
Autores principales: Voros, Orsolya, Panyi, György, Hajdu, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583858/
https://www.ncbi.nlm.nih.gov/pubmed/34768945
http://dx.doi.org/10.3390/ijms222111514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583858/
https://www.ncbi.nlm.nih.gov/pubmed/34768945
http://dx.doi.org/10.3390/ijms222111514

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