Gene Therapy Strategy for Alzheimer’s and Parkinson’s Diseases Aimed at Preventing the Formation of Neurotoxic Oligomers in SH-SY5Y Cells

We present here a gene therapy approach aimed at preventing the formation of Ca(2+)-permeable amyloid pore oligomers that are considered as the most neurotoxic structures in both Alzheimer’s and Parkinson’s diseases. Our study is based on the design of a small peptide inhibitor (AmyP53) that combine...

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Detalles Bibliográficos
Autores principales: El-Battari, Assou, Rodriguez, Léa, Chahinian, Henri, Delézay, Olivier, Fantini, Jacques, Yahi, Nouara, Di Scala, Coralie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583875/
https://www.ncbi.nlm.nih.gov/pubmed/34768981
http://dx.doi.org/10.3390/ijms222111550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583875/
https://www.ncbi.nlm.nih.gov/pubmed/34768981
http://dx.doi.org/10.3390/ijms222111550

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