The Peripheral Role of CCL2 in the Anti-Nociceptive Effect of Sigma-1 Receptor Antagonist BD1047 on Inflammatory Hyperalgesia in Rats

Our recent study demonstrated that the CC-chemokine ligand 2 (CCL2) present in primary afferent fibers (PAFs) plays an important role in the microglia-dependent neuronal activation associated with zymosan-induced inflammatory pain. The present study was aimed to evaluate whether BD1047 (a prototypic...

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Detalles Bibliográficos
Autores principales: Chun, Sungkun, Lee, Jun-Ho, Yoon, Seo-Yeon, Kwon, Young-Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583891/
https://www.ncbi.nlm.nih.gov/pubmed/34769165
http://dx.doi.org/10.3390/ijms222111730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583891/
https://www.ncbi.nlm.nih.gov/pubmed/34769165
http://dx.doi.org/10.3390/ijms222111730

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