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NLRP3 Inflammasome Blocking as a Potential Treatment of Central Insulin Resistance in Early-Stage Alzheimer’s Disease

Background: Alzheimer’s disease (AD) is a devastating neurodegenerative disorder. In recent years, attention of researchers has increasingly been focused on studying the role of brain insulin resistance (BIR) in the AD pathogenesis. Neuroinflammation makes a significant contribution to the BIR due t...

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Detalles Bibliográficos
Autores principales: Komleva, Yulia K., Potapenko, Ilia V., Lopatina, Olga L., Gorina, Yana V., Chernykh, Anatoly, Khilazheva, Elena D., Salmina, Alla B., Shuvaev, Anton N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583950/
https://www.ncbi.nlm.nih.gov/pubmed/34769018
http://dx.doi.org/10.3390/ijms222111588