Cargando…

NLRP3 Inflammasome Blocking as a Potential Treatment of Central Insulin Resistance in Early-Stage Alzheimer’s Disease

Background: Alzheimer’s disease (AD) is a devastating neurodegenerative disorder. In recent years, attention of researchers has increasingly been focused on studying the role of brain insulin resistance (BIR) in the AD pathogenesis. Neuroinflammation makes a significant contribution to the BIR due t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Komleva, Yulia K., Potapenko, Ilia V., Lopatina, Olga L., Gorina, Yana V., Chernykh, Anatoly, Khilazheva, Elena D., Salmina, Alla B., Shuvaev, Anton N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583950/ https://www.ncbi.nlm.nih.gov/pubmed/34769018 http://dx.doi.org/10.3390/ijms222111588

Ejemplares similares

Inflamm-Aging and Brain Insulin Resistance: New Insights and Role of Life-style Strategies on Cognitive and Social Determinants in Aging and Neurodegeneration
por: Komleva, Yulia, et al.
Publicado: (2021)

Neurobiological Aspects of Face Recognition: The Role of Oxytocin
por: Lopatina, Olga L., et al.
Publicado: (2018)

Blood–Brain Barrier and Neurovascular Unit In Vitro Models for Studying Mitochondria-Driven Molecular Mechanisms of Neurodegeneration
por: Salmina, Alla B., et al.
Publicado: (2021)

Early Life Stress and Metabolic Plasticity of Brain Cells: Impact on Neurogenesis and Angiogenesis
por: Salmina, Alla B., et al.
Publicado: (2021)

H(2)S- and NO-Signaling Pathways in Alzheimer's Amyloid Vasculopathy: Synergism or Antagonism?
por: Salmina, Alla B., et al.
Publicado: (2015)

Differential Roles of Environmental Enrichment in Alzheimer’s Type of Neurodegeneration and Physiological Aging
por: Salmin, Vladimir V., et al.
Publicado: (2017)

Plasticity of Adipose Tissue-Derived Stem Cells and Regulation of Angiogenesis
por: Panina, Yulia A., et al.
Publicado: (2018)

CD157 and Brain Immune System in (Patho)physiological Conditions: Focus on Brain Plasticity
por: Lopatina, Olga L., et al.
Publicado: (2020)

Endothelial Progenitor Cells Physiology and Metabolic Plasticity in Brain Angiogenesis and Blood-Brain Barrier Modeling
por: Malinovskaya, Natalia A., et al.
Publicado: (2016)

Protective Effect of Memantine on Bergmann Glia and Purkinje Cells Morphology in Optogenetic Model of Neurodegeneration in Mice
por: Shuvaev, Anton N., et al.
Publicado: (2021)

Designing in vitro Blood-Brain Barrier Models Reproducing Alterations in Brain Aging
por: Osipova, Elena D., et al.
Publicado: (2018)

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
por: Saresella, Marina, et al.
Publicado: (2016)

Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1
por: Shuvaev, Anton N., et al.
Publicado: (2022)

The Role of Microglia and the Nlrp3 Inflammasome in Alzheimer's Disease
por: Hanslik, Kendra L., et al.
Publicado: (2020)

Activation of NLRP3 Inflammasome and Onset of Alzheimer’s Disease
por: Bai, Hua, et al.
Publicado: (2021)

Insulin Reduces Inflammation by Regulating the Activation of the NLRP3 Inflammasome
por: Chang, Yu-Wei, et al.
Publicado: (2021)

The Roles of Oxytocin and CD38 in Social or Parental Behaviors
por: Lopatina, Olga, et al.
Publicado: (2013)

Loganin Prevents Hepatic Steatosis by Blocking NLRP3 Inflammasome Activation
por: Jang, Joo Hyeon, et al.
Publicado: (2023)

The inhibitory effect of LPS on the expression of GPR81 lactate receptor in blood-brain barrier model in vitro
por: Boitsova, Elizaveta B., et al.
Publicado: (2018)

The NLRP6 inflammasome
por: Zheng, Danping, et al.
Publicado: (2020)

Inflammasome NLRP3 Potentially Links Obesity-Associated Low-Grade Systemic Inflammation and Insulin Resistance with Alzheimer’s Disease
por: Litwiniuk, Anna, et al.
Publicado: (2021)

NLRP3 inflammasome as a novel therapeutic target for Alzheimer’s disease
por: Zhang, Yun, et al.
Publicado: (2020)

Gender Differences of NLRP1 Inflammasome in Mouse Model of Alzheimer's Disease
por: Zhang, Jinghang, et al.
Publicado: (2020)

Pharmacological and Epigenetic Regulators of NLRP3 Inflammasome Activation in Alzheimer’s Disease
por: La Rosa, Francesca, et al.
Publicado: (2021)

The Role of NLRP3 Inflammasome in Alzheimer’s Disease and Potential Therapeutic Targets
por: Liang, Tao, et al.
Publicado: (2022)

Interaction between autophagy and the NLRP3 inflammasome in Alzheimer’s and Parkinson’s disease
por: Lu, Ranran, et al.
Publicado: (2022)

Extracellular S100β Disrupts Bergman Glia Morphology and Synaptic Transmission in Cerebellar Purkinje Cells
por: Belozor, Olga S., et al.
Publicado: (2019)

YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3
por: Wang, Dan, et al.
Publicado: (2021)

CD38 in the nucleus accumbens and oxytocin are related to paternal behavior in mice
por: Akther, Shirin, et al.
Publicado: (2013)

Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis
por: Cai, Yawen, et al.
Publicado: (2022)

Communication Impairment in Ultrasonic Vocal Repertoire during the Suckling Period of Cd157 Knockout Mice: Transient Improvement by Oxytocin
por: Lopatina, Olga L., et al.
Publicado: (2017)

Inhibiting the NLRP3 Inflammasome
por: El-Sharkawy, Lina Y., et al.
Publicado: (2020)

Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease
por: Youm, Yun-Hee, et al.
Publicado: (2015)

Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation
por: Darweesh, Mahmoud, et al.
Publicado: (2019)

The NALP3/NLRP3 Inflammasome Instigates Obesity-Induced Autoinflammation and Insulin Resistance
por: Vandanmagsar, Bolormaa, et al.
Publicado: (2011)

Research Progress of Mitochondrial Mechanism in NLRP3 Inflammasome Activation and Exercise Regulation of NLRP3 Inflammasome
por: Zhang, Tan, et al.
Publicado: (2021)

Alzheimer’s Disease: New Concepts on the Role of Autoimmunity and NLRP3 Inflammasome in the Pathogenesis of the Disease
por: Severini, Cinzia, et al.
Publicado: (2021)

The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney
por: Kim, Yang Gyun, et al.
Publicado: (2019)

Diverse viral proteases activate the NLRP1 inflammasome
por: Tsu, Brian V, et al.
Publicado: (2021)

Neuroinflammation and Infection: Molecular Mechanisms Associated with Dysfunction of Neurovascular Unit
por: Tohidpour, Abolghasem, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hdfga05gav7jo06kv4h4g5ul9a