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Proteasome Inhibitors and Their Pharmacokinetics, Pharmacodynamics, and Metabolism

The proteasome is responsible for mediating intracellular protein degradation and regulating cellular function with impact on tumor and immune effector cell biology. The proteasome is found predominantly in two forms, the constitutive proteasome and the immunoproteasome. It has been validated as a t...

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Detalles Bibliográficos
Autores principales: Wang, Jinhai, Fang, Ying, Fan, R. Andrea, Kirk, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583966/
https://www.ncbi.nlm.nih.gov/pubmed/34769030
http://dx.doi.org/10.3390/ijms222111595