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Proteasome Inhibitors and Their Pharmacokinetics, Pharmacodynamics, and Metabolism
The proteasome is responsible for mediating intracellular protein degradation and regulating cellular function with impact on tumor and immune effector cell biology. The proteasome is found predominantly in two forms, the constitutive proteasome and the immunoproteasome. It has been validated as a t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583966/ https://www.ncbi.nlm.nih.gov/pubmed/34769030 http://dx.doi.org/10.3390/ijms222111595 |