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Pathogenic Variants in Selenoproteins and Selenocysteine Biosynthesis Machinery

Selenium is incorporated into selenoproteins as the 21st amino acid selenocysteine (Sec). There are 25 selenoproteins encoded in the human genome, and their synthesis requires a dedicated machinery. Most selenoproteins are oxidoreductases with important functions in human health. A number of disorde...

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Detalles Bibliográficos
Autores principales: Santesmasses, Didac, Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584023/
https://www.ncbi.nlm.nih.gov/pubmed/34769022
http://dx.doi.org/10.3390/ijms222111593