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Pathogenic Variants in Selenoproteins and Selenocysteine Biosynthesis Machinery
Selenium is incorporated into selenoproteins as the 21st amino acid selenocysteine (Sec). There are 25 selenoproteins encoded in the human genome, and their synthesis requires a dedicated machinery. Most selenoproteins are oxidoreductases with important functions in human health. A number of disorde...
Autores principales: | Santesmasses, Didac, Gladyshev, Vadim N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584023/ https://www.ncbi.nlm.nih.gov/pubmed/34769022 http://dx.doi.org/10.3390/ijms222111593 |
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