Cargando…

Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase

Ribosome-inactivating proteins (RIPs) hydrolyze the N-glycosidic bond and depurinate a specific adenine residue (A-4324 in rat 28S ribosomal RNA, rRNA) in the conserved α-sarcin/ricin loop (α-SRL) of rRNA. In this study, we have purified and characterized lyophyllin, an unconventional RIP from Lyoph...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Jia-Qi, Shi, Wei-Wei, Xiao, Meng-Jie, Tang, Yun-Sang, Zheng, Yong-Tang, Shaw, Pang-Chui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584072/
https://www.ncbi.nlm.nih.gov/pubmed/34769028
http://dx.doi.org/10.3390/ijms222111598