Isoform-Specific Effects of Apolipoprotein E on Hydrogen Peroxide-Induced Apoptosis in Human Induced Pluripotent Stem Cell (iPSC)-Derived Cortical Neurons

Hydrogen peroxide (H(2)O(2))-induced neuronal apoptosis is critical to the pathology of Alzheimer’s disease (AD) as well as other neurodegenerative diseases. The neuroprotective effects of apolipoprotein (ApoE) isoforms against apoptosis and the underlying mechanism remains controversial. Here, we h...

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Detalles Bibliográficos
Autores principales: Gao, Huiling, Zheng, Wei, Li, Cheng, Xu, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584079/
https://www.ncbi.nlm.nih.gov/pubmed/34769014
http://dx.doi.org/10.3390/ijms222111582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584079/
https://www.ncbi.nlm.nih.gov/pubmed/34769014
http://dx.doi.org/10.3390/ijms222111582

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