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In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia

Recent studies suggest that treatment with SGLT-2 inhibitors can reduce hepatic lipid storage and ameliorate non-alcoholic fatty liver disease (NAFLD) development beyond their glycemic benefits. However, the exact mechanism involved is still unclear. We investigated the hepatic metabolic effect of e...

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Detalles Bibliográficos
Autores principales: Hüttl, Martina, Markova, Irena, Miklankova, Denisa, Zapletalova, Iveta, Poruba, Martin, Haluzik, Martin, Vaněčkova, Ivana, Malinska, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584090/
https://www.ncbi.nlm.nih.gov/pubmed/34768942
http://dx.doi.org/10.3390/ijms222111513