Differential p53-Mediated Cellular Responses to DNA-Damaging Therapeutic Agents

The gene TP53, which encodes the tumor suppressor protein p53, is mutated in about 50% of cancers. In response to cell stressors like DNA damage and after treatment with DNA-damaging therapeutic agents, p53 acts as a transcription factor to activate subsets of target genes which carry out cell fates...

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Detalles Bibliográficos
Autores principales: Carlsen, Lindsey, El-Deiry, Wafik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584119/
https://www.ncbi.nlm.nih.gov/pubmed/34769259
http://dx.doi.org/10.3390/ijms222111828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584119/
https://www.ncbi.nlm.nih.gov/pubmed/34769259
http://dx.doi.org/10.3390/ijms222111828

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