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PARP-1-Associated Pathological Processes: Inhibition by Natural Polyphenols

Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme involved in processes of cell cycle regulation, DNA repair, transcription, and replication. Hyperactivity of PARP-1 induced by changes in cell homeostasis promotes development of chronic pathological processes leading to cell death during v...

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Detalles Bibliográficos
Autores principales: Maluchenko, Natalya V., Feofanov, Alexey V., Studitsky, Vasily M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584120/
https://www.ncbi.nlm.nih.gov/pubmed/34768872
http://dx.doi.org/10.3390/ijms222111441